Nucleosome knowledge base (beta)
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Any nucleosome
(H3)
Histone H3 with a methionine substitution for lysine-27
H3K27M
Histone H4 lysine-16 acetylation
H4K16ac
Histone variant H2A.Z
H2A.Z
Nucleosome with at least histone H3 lysine-4 trimethylation and histone H4 lysine-16 acetylation
(H3K4me3·H4K16ac)
Tetrasome
(H3·H4·{H2A}0·{H2B}0)
Two nucleosomes 30 bp apart, one acetylated at histone H4 lysine-16
(H4K16ac)-30-(H4)
Histone dimer in mixed and stylized notation
H2A-S1ph/K5ac@H2B:K12ac/K15ac,K20ac
Dinucleosome array with a ubiquitinated nucleosome
(H3K27M)(H3K36M·H2BK120ub)
Histone H3 lysine-27 trimethylation and lysine-36 trimethylation
H3K27me3K36me3
Nucleosome exactly with two homotypic histone H3 lysine-9 trimethylations
([H3K9me3]2)
Histone H3 with no methylation at lysine-27
H3K27me0
Hexasome
([H2A·H2B]·{H2A·H2B}0·H3·H4)
Penta-acetylated histone H3 with histone H4 lysine-16 acetylation
(H3K9acK14acK18acK23acK27ac·H4K16ac)
Penta-acetylated histone H3 with penta-acetylated histone H4
(H3K9acK14acK18acK23acK27ac·H4K5acK8acK12acK16acK20ac)
(H3)
Histone H3 with a methionine substitution for lysine-27H3K27M
Histone H4 lysine-16 acetylationH4K16ac
Histone variant H2A.ZH2A.Z
Nucleosome with at least histone H3 lysine-4 trimethylation and histone H4 lysine-16 acetylation(H3K4me3·H4K16ac)
Tetrasome(H3·H4·{H2A}0·{H2B}0)
Two nucleosomes 30 bp apart, one acetylated at histone H4 lysine-16(H4K16ac)-30-(H4)
Histone dimer in mixed and stylized notationH2A-S1ph/K5ac@H2B:K12ac/K15ac,K20ac
Dinucleosome array with a ubiquitinated nucleosome(H3K27M)(H3K36M·H2BK120ub)
Histone H3 lysine-27 trimethylation and lysine-36 trimethylationH3K27me3K36me3
Nucleosome exactly with two homotypic histone H3 lysine-9 trimethylations([H3K9me3]2)
Histone H3 with no methylation at lysine-27H3K27me0
Hexasome([H2A·H2B]·{H2A·H2B}0·H3·H4)
Penta-acetylated histone H3 with histone H4 lysine-16 acetylation(H3K9acK14acK18acK23acK27ac·H4K16ac)
Penta-acetylated histone H3 with penta-acetylated histone H4(H3K9acK14acK18acK23acK27ac·H4K5acK8acK12acK16acK20ac)
Look up histone positions, mutations, and PTMs using Keogh notation.
- Single position —
H3K27 - Substitution —
H3K27M - PTM —
H4K20me3 - Nucleosome —
(H3K27M H4K16ac) - Heterotypic nucleosomes —
(H3K27M H4K16ac H4K5ac) - Multiple nucleosomes —
(H3K27M)(H3K36me3)
Use : to separate family from position
(H3:K27M) and @ to separate histones
(H3:K27M @ H4:K16ac) when the compact form is ambiguous.